Provigil (Modafinil Australia) is a wakefulness-promoting drug approved by the FDA to treat excessive sleepiness caused by narcolepsy, obstructive sleep apnea/hypopnea syndrome and shift work disorder. It also has a variety of other uses and is available in generic form.
Two US 9-week, placebo-controlled clinical studies of patients with narcolepsy showed that Modafinil 200 mg and 400 mg significantly improved objective and subjective measures of excessive sleepiness compared to placebo.
How Does Modvigil Work?
Some people have sleep disorders that make them feel very tired during the day, a condition called excessive daytime sleepiness (EDS). Provigil and other medicines like it improve wakefulness by changing the amounts of natural substances in the brain that control sleep and wakefulness.
Modafinil is also used off-label to enhance cognitive performance and increase focus, which makes it a popular choice for students, executives, and anyone who needs to stay awake during the day. However, it is important to know that the drug can be addictive if used over a long period of time.
The typical dose of Modvigil 200 mg milligrams taken once a day in the morning. It is typically prescribed for chronic conditions such as narcolepsy and sleep apnea. It is also given to people who work night shifts and have shift work sleep disorder, which is usually taken about an hour before their shift starts. People with liver problems may need to take a lower dose than this.
Does Modvigil Work for Narcolepsy?
Narcolepsy is a chronic disorder of sleep/wake regulation characterized by excessive daytime sleepiness and other symptoms such as epsidal episodes, cataplexy, and hypnagogic hallucinations. The onset of these symptoms is unpredictable and can impact work, school, and social life. A GP or specialist can prescribe medicines called stimulants (such as modafinil, pitolisant and solriamfetol) to help keep you awake.
Provigil and the related medicine, armodafinil, are wakefulness-promoting agents used to treat sleep disorders such as narcolepsy, shift work sleep disorder and obstructive sleep apnea. It helps you stay alert, reduces fatigue and improves your ability to function during the day.
Both medications are effective at improving wakefulness in people with narcolepsy and other sleep disorders. In two multicenter, placebo-controlled clinical trials, both 200 mg and 400 mg doses of Provigil showed statistically significant improvement in a measure of wakefulness called the Maintenance of Wakefulness Test (MWT) compared to placebo. In addition, both doses showed significant improvement in patients’ overall clinical condition as measured by the Clinical Global Impression of Change scale at their final visit.
Does Modvigil Work for Sleep Apnea?
Provigil is a brand name drug that contains the active ingredient modafinil. It has been approved by the Food and Drug Administration to treat excessive sleepiness caused by narcolepsy, obstructive sleep apnea, and shift work sleep disorder. It is also sometimes used off-label to improve wakefulness and cognitive performance.
Modvigil has been shown to significantly reduce subjective and objective measures of excessive daytime sleepiness in several clinical trials. It is typically prescribed in dosages of 200 milligrams (mg) taken once per day in the morning. Higher doses have been prescribed for shift work sleep disorder, but they do not appear to be more effective than 200 mg daily.
